Caris MPI Pharmaceutical Services
Accelerating the Delivery of Personalized Medicine
Driving targeted clinical trials and personalized therapy commercialization through world class biosample
management, unparalled translational medicine expertise, and customized assay and companion
diagnostic development.
Molecular Profiling and Custom Assay Development
- Customized immunohistochemistry
- FISH testing (including custom probes capabilities)
- Comprehensive DNA microarray analysis
- Sequence analysis
- Cancer cytogenetics
- SNP analysis
- DNA/RNA isolation
- Flow cytometry
- Cellular manipulation (serum separation, buffy coat isolation, and cell sorting)
- Light microscopy
- PCR / qPCR / RT-qPCR
- aCGH analysis
- Proteomic analysis
- Western blot analysis
- Circulating tumor cell analysis
Companion Diagnostics
Target Identification
• Biomarker identification
• Diagnostic and prognostic algorithm development
• Assay optimization and validation
Diagnostic Development
• Parallel development with targeted therapeutic
• CLIA validation
• Kit development
Bio-specimen Collection and Clinical Trial Support
Clinical Channels
• Access to over 7million patients through US Oncology partnership
Tracking and Reporting
• Secure and client specific web-based bio-specimen tracking and reporting system
• Top-tier clinical data management system tracks patient forms
• Laboratory information management system(LIMS) tracks bio-specimen manipulation activities
Secure and Comprehensive Storage
• Multi-temperature storage capabilities
• Liquid nitrogen vapor, -145°, -80°, -20°, and 4° Celsius
• State of the art CryoPort liquid nitrogen shipments
• 24/7 temperature monitoring
• Complete IT solution with LIMS and tracking
• Rapid turnaround sample retrieval and distribution
Computing Power
• Custom software design
• Secure, web-enabled, customer login for reports, digital files and images
Logistical Support
• Custom kit and collection instruction preparation
• Bio-specimen collection & redistribution
• Bio specimen tracking - label design / bar coding
• IATA certified shippers
• Availability of US Oncology Central Pharmacy for kit distribution
World-class pharmaceutical sponsors, research organizations and diagnostics companies partner with Caris MPI on pivotal clinical trials
- Abraxis Biosciences
- Agilent Technologies
- Biogen Idec
- Cell Therapeutics, Inc.
- Exelixis Pharmaceuticals
- Gen-Probe, Inc.
- The International Genomics Consortium(IGC)
- The National Cancer Institute (NCI)
- Roche
- Sanofi-Aventis
- Scottsdale Healthcare Research Center
- Systems Medicine, Inc.
- Texas Oncology P.A. (TOPA)
- Theradex
- TGen Drug Development Services (TD2)
- The Translational Genomics Research Institute (TGen)
- US Oncology
- Other
Caris MPI pharmaceutical services is US Oncology’s preferred laboratory for bio specimen collection and analysis in clinical trials
Our research and diagnostic heritage, academic credibility and scientific achievements allow Caris MPI to offer our clients earlier access to cutting edge technology and customized solutions that facilitate world class drug discovery and development.
Caris MPI Pharmaceutical Services serves as the preferred provider for all of the banking and molecular analysis within US Oncology’s national network-the largest oncology clinical trial network in the country. Twenty six (26) of the last thirty two (32) FDA-registered oncology drugs were developed through US Oncology’s network.
Our Research Partners:
- US Oncology
- The International Genomics Consortium (IGC)
- The Translational Genomics Research Institute (Tgen)
- The Biodesign Institute at Arizona State University